165. Structure-Based Virtual Screening and De Novo Design to Identify Submicromolar Inhibitors of G2019S mutant of Leucine-Rich Repeat Kinase 2

Park, H.; Kim, T.; Kim, K.; Jang, A.; Hong, S.* 

Int. J. Mol. Sci. 2022, 123, 12825.

164. Site-Selective Pyridine C–H Alkylation with Alcohols and Thiols via Single-Electron Transfer of Frustrated Lewis Pairs 

Tan, C.-Y.; Kim, M.; Park, I.; Kim, Y.; Hong, S.* 

Angew. Chem. Int. Ed. 2022, 61, e20221385

163. Photocatalytic Decarboxylative Pyridylation of Carboxylic Acids Using In Situ-Generated Amidyl Radicals as Oxidants

Kim, C.; Jeong, J.; Vellakkaran, M.; Hong, S.* 

ACS Catal. 2022, 12, 13225.

Highlighted in Synfacts 2023, 19(01), 0053.  

162. A novel DDR1 Inhibitor Enhances the Anticancer Activity of Gemcitabine in Pancreatic Cancer

Ko, S.; Jung, K.-H.; Yoon, Y.-C.; Han, B. S.; Park, M. S.; Lee, Y. J.; Kim, S. E.; Cho, Y. J.; Ryu, J. K.; Kim, K.; Kim, T. Y.; Hong, S.*; Lee, S. H.*; Hong, S.-S.*

Am. J. Cancer Res. 2022, 12, 4326.

161. N-Functionalized Pyridinium salts: A New Chapter for Site-Selective Pyridine C–H Functionalization via Radical-Based Processes under Visible Light Irradiation 

Kim, M.; Koo, Y.; Hong, S.*  

Acc. Chem. Res. 2022, 55, 3043.

160. Two-Track Virtual Screening Approach to Identify the Dual Inhibitors of Wild Type and C481S Mutant of Bruton’s Tyrosine Kinase

Kim, T.;  Kim, K.; Park, I.; Hong, S.*; Park, H.*

J. Chem. Inf. Model. 2022, 62, 4500.  

159. Oxidatively Induced Reactivity in Rh(III)-Catalyzed 7-Azaindole Synthesis: Insights into the Role of the Silver Additive

Ryu, H.; Pudasaini, B.: Cho, D.; Hong, S.*; Baik, M.-H.* 

Chem. Sci. 2022, 13, 10707.

158. Site-Selective Pyridylic C–H Functionalization by Photocatalytic Radical Cascades 

Kim, M.; You, E.; Kim, J.; Hong, S.* 

Angew. Chem. Int. Ed. 2022, 61, e202204217.

Highlighted as a Front Cover

Selected as a Hot Paper 

157. Nickel-Catalyzed Regio- and Enantioselective Hydroamination of Unactivated Alkenes Using Carbonyl Directing Groups 

Lee, C.; Kang, H. J.; Seo, H.; Hong, S.* 

J. Am. Chem. Soc. 2022, 144, 9091.

Highlighted in Synfacts 2022, 18(08), 0935. 

Highlighted in Organic Chem Portal.  

156. Discovery of a novel NUAK1 inhibitor against pancreatic cancer through inhibition of PI3K/AKT pathway

Seo, M .S.: Jung, K. H.; Kim, K.; Lee, J. E.; Han, B. S.; Ko, S.; Hong, S.*; Lee, S. H.*; Hong, S.-S.*

Biomed. Pharmacother. 2022, 152, 113241.